Effect of CFTR_inh-172 on <i>V.</i><i>cholerae</i>-induced intestinal fluid secretion in adult mice.

<p>After inoculation of <i>V. cholerae</i> into ileal loops, 20 µg of CFTR_inh-172 was administered into mouse peritoneal cavity every 6 h. At 12 h after <i>V. cholerae</i> challenge, ileal loops were removed for measurement of loop weight/length ratio. (A) Representative photographs of ileal loops after indicated treatments. (B) Loop weight/length ratio with indicated treatments. Data were expressed as mean ± S.E. (n = 4). ***, P<0.01 compared with <i>V. cholerae</i>-inoculated control.