Results from whole brain-based spatial statistics (WBSS) of MD-, AD-, and RD-maps of APP mice vs. wt mice at p<0.05, FDR corrected (coronal views).

<p>Reduction is displayed in hot colors. (A–E) MD reduction in the lateral septal nucleus, the dorsal hippocampues, the thalamus, the amygdala, and the internal capsule, respectively; (F–I) AD-reduction in the dorsal hippocampus (bihemispheric), the entorhinal cortex (bihemispheric), the dorsomedian hypothalamic nucleus region, and in the lateral septal nucleus, respectively; (J–M) RD-reduction in the cerebellum (bihemispheric), the lateral septal nucleus, the thalamus, and the dentate gyrus, respectively.