Anxiety is elevated in male Nrxn1α mice.

<p>Data shown are anxiety measures taken from the open field, light/dark box and elevated plus maze. Panels are mean (± sem) time spent in the central area of the open field for male (A) and female (B) Nrxn1α mice, time spent in the light compartment of the light/dark box for male (C) and female (D) Nrxn1α mice and time spent in the open arms of the elevated plus maze for male (E) and female (F) Nrxn1α mice. Data derived from 23 WT (12M, 11F) 29 HET (15M, 14F) 18 KO (9M, 9F) mice. Levels of significance indicated by *** as p<0.001, compared to WT mice, and ### as p<0.001, compared to HET mice.