EEG-fMRI results and Time-Frequency (TF) statistical maps of SEEG recordings from patient 3.

<p>A – Scalp EEG showing right temporo-parietal IED (spike and slow wave) and the associated BOLD changes. Most significant deactivation (t = -6.7) is in right IPL and concordant with the spike field. Smaller deactivations are in posterior pre-cuneus and frontal and parietal regions ipsilateral to the IED. Activations are in the cingulate gyri, thalami and ipsilateral central region. B - SEEG traces showing typical runs of spike and slow waves in right IPL (lower 3 traces) and in right PCC and middle cingulate (MC). C – TF plots comparing IEDs and baseline in PCC, MC and the channels with IEDs (IPL). The IPL is the spiking channel and part of the DMN. TF maps centered at the center of IED run show decrease in gamma in the channels with IEDs (IPL). Boxed TF map is shown in higher magnification on the right and demonstrates power decrease in 40–160 Hz band, and increase in frequencies <30 Hz.