<p>Sequence logos for selected kinase motifs in the FAM69 family. <i>Top:</i> the β-4 - β-5 region. <i>Middle row, left:</i> the predicted active site region (corresponding to D166 and N171 in PKA). <i>Middle row, right</i>- the Mg<sup>2+</sup> - binding motif (corresponding to the DFG motif in PKA). <i>Bottom, left:</i> predicted helix α-F. <i>Bottom, right:</i> predicted helix α-G.</p
Phosphorylation is the most widely studied post-translational modification occurring in cells. While...
Phosphorylation is the most widely studied post-translational modification occurring in cells. While...
<p>A) Phylogenetic tree for human MKK4, MKK7, MKK3, MKK6, MEK1, p38, JNK, and ERK. B) Amino acid seq...
<p><i>Left:</i> alignment of the kinase domain, covering the region 83–422 of FAM69A. The sequences ...
<p><i>Top left:</i> model coloured by MetaMQAP model quality score (blue: good quality, red: poor qu...
<p>These motif extraction results illustrate the inter-residue correlations found among the phosphor...
<p><b>A</b>. Sub-domains of the protein kinase domain. Consensus sequences DL(R/A)A(A/R)N in subdoma...
<p>Sequence logos for the conserved motifs of the SELO family (using the 143 representative sequence...
<p>(A) Sequence motif analysis was performed using IceLogo and motif-x. Amino acid sequences of diff...
Phosphorylation is the most widely studied post-translational modification occurring in cells. While...
Phosphorylation is the most widely studied post-translational modification occurring in cells. While...
The catalogues of protein kinases, the essential effectors of cellular signaling, have been charted ...
Phosphorylation is the most widely studied post-translational modification occurring in cells. While...
<p>Eukaryotic protein kinase regulation. Structural motifs in eukaryotic protein kinases adopt speci...
<p>Top 15 kinases predicted with high confidence to have a helix at part of the activation loop.</p
Phosphorylation is the most widely studied post-translational modification occurring in cells. While...
Phosphorylation is the most widely studied post-translational modification occurring in cells. While...
<p>A) Phylogenetic tree for human MKK4, MKK7, MKK3, MKK6, MEK1, p38, JNK, and ERK. B) Amino acid seq...
<p><i>Left:</i> alignment of the kinase domain, covering the region 83–422 of FAM69A. The sequences ...
<p><i>Top left:</i> model coloured by MetaMQAP model quality score (blue: good quality, red: poor qu...
<p>These motif extraction results illustrate the inter-residue correlations found among the phosphor...
<p><b>A</b>. Sub-domains of the protein kinase domain. Consensus sequences DL(R/A)A(A/R)N in subdoma...
<p>Sequence logos for the conserved motifs of the SELO family (using the 143 representative sequence...
<p>(A) Sequence motif analysis was performed using IceLogo and motif-x. Amino acid sequences of diff...
Phosphorylation is the most widely studied post-translational modification occurring in cells. While...
Phosphorylation is the most widely studied post-translational modification occurring in cells. While...
The catalogues of protein kinases, the essential effectors of cellular signaling, have been charted ...
Phosphorylation is the most widely studied post-translational modification occurring in cells. While...
<p>Eukaryotic protein kinase regulation. Structural motifs in eukaryotic protein kinases adopt speci...
<p>Top 15 kinases predicted with high confidence to have a helix at part of the activation loop.</p
Phosphorylation is the most widely studied post-translational modification occurring in cells. While...
Phosphorylation is the most widely studied post-translational modification occurring in cells. While...
<p>A) Phylogenetic tree for human MKK4, MKK7, MKK3, MKK6, MEK1, p38, JNK, and ERK. B) Amino acid seq...