Functional annotation of differentially expressed genes.

<p>(A) Based on RNA-Seq data, expression levels for 300 genes were found to be significantly changed in imidacloprid-exposed larvae (compared with data obtained from non-exposed larvae). Expression is reduced for 195 genes (blue); expression is increased for 105 genes (red). The group of over-expressed genes includes nine cytochrome <i>P450s</i>; their gene IDs and normalised fold-change values are shown in the table. (B) Selection of non-redundant Gene Ontology (GO) terms for the three ontologies: Biological Process (BP), Molecular Function (MF) and Cellular Component (CC), and Interpro (IP) protein domains that are overrepresented in the 105 up (red) and 195 down (blue) regulated genes. Significance of enrichment is based on Fisher’s Exact Test. GO terms for the most significant enrichment groups are indicated in bold letters.