Effect of chronic ICV ghrelin infusion on the dynamic parameters of histomorphometric analyses.

<p>(A–B) Dynamic histomorphometric analyses of lumbar spine, including mineral apposition rate (MAR) and bone formation rate (BFR). (C) Representative fluorescent images obtained from lumbar spine after calcein double labeling (100× magnification). Three groups of rats (4–6 per group) were infused for 21 days with saline or ghrelin (1.5 μg/day). Rats infused with ghrelin were <i>ad lib</i>-fed or pair-fed (to saline-infused rats). * P<0.05; Data are presented as the mean ± SEM.