Numbers and baseline characteristics of patients included in the meta-analysis.

<p>Baseline differences across the studies:¹(p = 0.001), the fraction of females in the study by Senet et al. is substantially smaller. ²(p = 0.07) no significant difference of patient age, ³(p<0.0001), significant larger ulcers were included in the study by Münter et al, ⁴(p = 0.002), the study by Humbert et al. included somewhat younger ulcers.