PrP<sup>Sc</sup> Detection by SOFIA Following PASA (sPMCA<sub>200</sub>) in urine and blood.
- Richard Rubenstein (313719)
- Binggong Chang (313712)
Publication date
July 2013
DOIAbstract
<p>PASA was evaluated in human urine and blood from each sCJD case and blood from vCJD-infected Tg666 mice. Following sPMCA<sub>200</sub>, samples were analyzed in triplicate by SOFIA for the presence of PrP<sup>Sc</sup>. Signal intensities from SOFIA were adjusted based on the dilution of samples throughout sPMCA<sub>200</sub>, calculated as the mean fluorescent signal±standard deviation and expressed as the signal/background ratio.</p
Add to ORKG