dnMAML decreases cartilage formation during fracture healing.

<p>(<b>A</b>) Percent of cartilage area to total callus area (CA/TA) via SafO histomorphometric analysis is decreased in dnMAML fractures at 10dpf. (<b>B</b>) Col2a1 and (<b>C</b>) Sox9 gene expression are decreased in dnMAML fractures at 10dpf. (<b>D</b>) ColX gene expression is non-significantly decreased in dnMAML fractures at 10dpf. (<b>E</b>) There are no differences between WT and dnMAML fractures in percent of immature, mature or hypertrophic cartilage to cartilage area (CA) at 10dpf. (<b>F</b>) There are no differences in chondrocyte density within these areas at 10dpf. SafO images were acquired at 20x magnification. Gene expression data is presented as relative expression to β-actin, calculated using the formula. 2^-ΔC(t). *p<0.050 ^tp<0.100 (dnMAML vs WT).