Radiofrequency generator and fiber optic probe placement.

<p><i>Panel A.</i> For fiberoptic thermography, a temperature-sensing probe is placed through a 20 G needle. The needle is advanced into the tumor (T) under ultrasound guidance. The probe is then advanced through the needle and the needle is withdrawn. <i>Panel B.</i> Kanzius 13.56 MHz external RF generator system is shown (black box) that is connected to an end-firing antenna in the transmission head (Tx). A spacing of 3.5 inches exists between the Tx head and the receiver head (Rx)/ground plate. <i>Panel C.</i> A CB17 SCID mouse is placed supine on the ground plate of the Rx head. A copper shield made from copper tape is used to ground all mice and prevent electrothermal injury. An abdominal window is created in the middle of the copper shield to allow RF field exposure to the tumor-bearing area.