<p>Caspase-3 activity in T84s was measured at 6 hpi and expressed as activity, measured in fluorescence focus units (FFU) per mg of protein. Measurements were carried out in the presence or absence of 10 µM MG132. Experiments were repeated at least three times in triplicate and data from a representative experiment is shown. Data was analyzed by an unpaired Student’s <i>t</i>-test. NS = Not significant.</p
<p>A cellular Ubi(G76V)-GFP proteasome assay was performed to measure the effect of α-syn on proteas...
<p>In each assay 50 µg of whole cell liver lysates from physiologically age-matched young mice (4 mo...
<p>HEK293T cell extract was treated with increasing concentrations of the indicated compound for 30-...
<p>(A) Cell death of RAW 264.7 cells at 6 hours post infection (hpi). The percentage of dead cells w...
<p>(A) Recovery of bacteria post intracellular survival and growth in BMDCs. After infection of BMDC...
<p>(A) The effect of inhibition of E1 ubiquitin activating enzymes on caspase-3 accumulation. RAW 26...
<p><b>A</b>: Chymotrypsin-like, caspase-like, and trypsin-like activities were measured in the lysat...
<p><b>A.</b> caspase-like, <b>B.</b> chymotrypsin-like, and <b>C.</b> trypsin-like activity of monol...
<p>RAW 264.7 cells were infected with LF82 and treated with or without the proteasomal inhibitor MG1...
<p>Spectrophotometry results of caspase 3 activity indicated that after exposure to these sulphamoyl...
<p><b>A–C:</b> HDAC3 inhibitors inhibit proteasome activity. Three different HDAC3 inhibitors were a...
<p>The cells were treated with IFN-γ (250 U/ml) for 24–96 hrs, lysed with triton X-100, and then sub...
<p>INS-1E Cells were cultured for 48 hours with an optimal 10 mM (G10) or a high 33 mM (G33) glucose...
<p>The same cells from Figure 2 were cultured in KH without (<b>A</b>) or with (<b>B</b>) amino acid...
<p>Multiple increases in caspase-3 activity in cells after treatment with 10 µg/mL of extracts for 4...
<p>A cellular Ubi(G76V)-GFP proteasome assay was performed to measure the effect of α-syn on proteas...
<p>In each assay 50 µg of whole cell liver lysates from physiologically age-matched young mice (4 mo...
<p>HEK293T cell extract was treated with increasing concentrations of the indicated compound for 30-...
<p>(A) Cell death of RAW 264.7 cells at 6 hours post infection (hpi). The percentage of dead cells w...
<p>(A) Recovery of bacteria post intracellular survival and growth in BMDCs. After infection of BMDC...
<p>(A) The effect of inhibition of E1 ubiquitin activating enzymes on caspase-3 accumulation. RAW 26...
<p><b>A</b>: Chymotrypsin-like, caspase-like, and trypsin-like activities were measured in the lysat...
<p><b>A.</b> caspase-like, <b>B.</b> chymotrypsin-like, and <b>C.</b> trypsin-like activity of monol...
<p>RAW 264.7 cells were infected with LF82 and treated with or without the proteasomal inhibitor MG1...
<p>Spectrophotometry results of caspase 3 activity indicated that after exposure to these sulphamoyl...
<p><b>A–C:</b> HDAC3 inhibitors inhibit proteasome activity. Three different HDAC3 inhibitors were a...
<p>The cells were treated with IFN-γ (250 U/ml) for 24–96 hrs, lysed with triton X-100, and then sub...
<p>INS-1E Cells were cultured for 48 hours with an optimal 10 mM (G10) or a high 33 mM (G33) glucose...
<p>The same cells from Figure 2 were cultured in KH without (<b>A</b>) or with (<b>B</b>) amino acid...
<p>Multiple increases in caspase-3 activity in cells after treatment with 10 µg/mL of extracts for 4...
<p>A cellular Ubi(G76V)-GFP proteasome assay was performed to measure the effect of α-syn on proteas...
<p>In each assay 50 µg of whole cell liver lysates from physiologically age-matched young mice (4 mo...
<p>HEK293T cell extract was treated with increasing concentrations of the indicated compound for 30-...