<p>The values are the average spurious association rate for ten run using 1,000 cases and controls from the European Americans in the Exome Sequencing Project. These are the rates at the 5% significance threshold for parameters defined as odds ratios (ORs) of 1/5, 1, or 5 for a fourth, half, or full distance between the minimum and maximum for each axis: PC1 are the columns, and PC2 are the probabilities calculated for each individual. Smaller values indicate larger differences in disease risk among individuals in PC space.</p
Plot over number of shared candidate disease-causing variants when successively adding up to 11 affe...
<p>Association results for variants showing the smallest <i>P</i>-values (top SNPs) in 31 regions su...
<p>Empty cells mean no significant association.</p><p><sup>a</sup> Chi-square value. Asterisks indic...
<p>Each square represents a confounding scenario set by different values of disease risks, parameter...
Advances in next-generation sequencing technology have enabled systematic exploration of the contrib...
Advances in next-generation sequencing technology have enabled systematic exploration of the contrib...
<p>Among 242,221 single nucleotide polymorphisms, only 15 SNPs significant to pathologic Gleason sco...
Genome-wide association studies are used to detect association between genetic variants and diseases...
1<p>minor allele2</p><p>minor allele frequency.</p>3<p>p-value corrected with Bonferroni correction....
<p>OR: odds ratio, CI: confidence interval, n/a: not applicable (heterogeneity I<sup>2</sup> confide...
<p>Each point represents a separate study for the indicated association. Log[OR], natural logarithm ...
Log(-values) are plotted for the 150-kb region showing the strongest association.<p><b>Copyright inf...
(A) Overlap between genes with candidate SNPs identified using different methods in the exome: linea...
Clinical & Investigative Medicine (CIM) is receiving an increasing number of reports of candidate-ba...
<p><b>Note:</b> MAF, minor allele frequency. UTR, untranslated region;</p>a<p>Odds ratio followed by...
Plot over number of shared candidate disease-causing variants when successively adding up to 11 affe...
<p>Association results for variants showing the smallest <i>P</i>-values (top SNPs) in 31 regions su...
<p>Empty cells mean no significant association.</p><p><sup>a</sup> Chi-square value. Asterisks indic...
<p>Each square represents a confounding scenario set by different values of disease risks, parameter...
Advances in next-generation sequencing technology have enabled systematic exploration of the contrib...
Advances in next-generation sequencing technology have enabled systematic exploration of the contrib...
<p>Among 242,221 single nucleotide polymorphisms, only 15 SNPs significant to pathologic Gleason sco...
Genome-wide association studies are used to detect association between genetic variants and diseases...
1<p>minor allele2</p><p>minor allele frequency.</p>3<p>p-value corrected with Bonferroni correction....
<p>OR: odds ratio, CI: confidence interval, n/a: not applicable (heterogeneity I<sup>2</sup> confide...
<p>Each point represents a separate study for the indicated association. Log[OR], natural logarithm ...
Log(-values) are plotted for the 150-kb region showing the strongest association.<p><b>Copyright inf...
(A) Overlap between genes with candidate SNPs identified using different methods in the exome: linea...
Clinical & Investigative Medicine (CIM) is receiving an increasing number of reports of candidate-ba...
<p><b>Note:</b> MAF, minor allele frequency. UTR, untranslated region;</p>a<p>Odds ratio followed by...
Plot over number of shared candidate disease-causing variants when successively adding up to 11 affe...
<p>Association results for variants showing the smallest <i>P</i>-values (top SNPs) in 31 regions su...
<p>Empty cells mean no significant association.</p><p><sup>a</sup> Chi-square value. Asterisks indic...