Extinction and reinstatement of the operant response for sucrose.

<p><b>A)</b> Average active lever presses during Stable FR1 and the final 2 days of extinction. Both genotypes significantly decreased their active lever presses during both days of extinction. <b>B)</b> Average active lever presses during extinction and cue-induced reinstatement. Both genotypes increased their active lever pressing in the reinstatement test following extinction. Data (mean±SEM) analysed using two-way RM ANOVA, followed by one-way ANOVA split by the factor ‘genotype’ with a Bonferroni correction. Significant effects of ‘day’ (<i>vs.</i> Stable FR1) are represented by “#” (^##<i>p</i><.01; ^###<i>p</i><.001). Abbreviations: EXT - final extinction score; FR1– fixed ratio 1; Reinst - reinstatement.