The application of acyclic <i>C</i><sub>2</sub>-symmetric chelating bis-sulfoxide ligands in the Rh(I)-catalyzed enantioselective 1,4-addition of boronic acids to electron-deficient alkenes is reported. Among the acyclic ethane-bridged bis-sulfoxides tested, the ligand Ferbisox (<b>11</b>), bearing ferrocenyl moieties as substituents at the sulfinyl sulfurs, has exhibited the best results in terms of chemical yield (up to 96%) and enantioselectivity (up to 97% ee). The conjugate addition takes place smoothly in toluene at room temperature in short reaction times (typically 2 h). The reaction scope, including the use of different boronic acids, five-, six-, and seven-membered cyclic enones, an unsaturated lactone, and the most challenging a...
International audienceThe rational use of directed deprotometallation, sulfur oxidation and sulfoxid...
A new family of sulfinamide/sulfoxide derivatives was synthesized as chiral bidentate ligands by ste...
A stereodivergent synthesis using inexpensive reagents, i.e., dibenzazepine and glucose-derived t-Bu...
The application of acyclic <i>C</i><sub>2</sub>-symmetric chelating bis-sulfoxide ligands in the Rh...
A novel chiral disulfoxide ligand pair bearing fluorine atoms at the 6 and 6′ position of its atropi...
A bis-sulfoxide with a binaphthyl backbone is introduced as a readily available, chiral ligand entit...
Deprotonation of phenyldibenzo[b,f]tropylidene (8) with LDA/t-BuOK followed by quenching with either...
A class of chiral sulfoxide-olefins were designed and synthesized through concise routes. Their appl...
A series of axially chiral bis-sulfoxide ligands have been efficiently synthesized via oxidative cou...
Synthesis of novel C<sub>2</sub>-symmetric 1,2- 1,3- and 1,4- bis-sulfinamides and their use as effe...
A Class of Benzene Backbone-Based Olefin-Sulfoxide Ligands for Rh-Catalyzed Enantioselective Additio...
Synthesis of novel C-2-symmetric 1,2-1,3- and 1,4-bis-sulfinamides and their use as effective ligand...
Disulfoxides with atropisomeric backbones are introduced as readily available chiral ligands for the...
At last! The addition of bisulfite to olefins, discovered over a century ago, remains the most strai...
An efficient Rh-catalyzed addition of arylboronic acids to N-tosylarylimines has been developed with...
International audienceThe rational use of directed deprotometallation, sulfur oxidation and sulfoxid...
A new family of sulfinamide/sulfoxide derivatives was synthesized as chiral bidentate ligands by ste...
A stereodivergent synthesis using inexpensive reagents, i.e., dibenzazepine and glucose-derived t-Bu...
The application of acyclic <i>C</i><sub>2</sub>-symmetric chelating bis-sulfoxide ligands in the Rh...
A novel chiral disulfoxide ligand pair bearing fluorine atoms at the 6 and 6′ position of its atropi...
A bis-sulfoxide with a binaphthyl backbone is introduced as a readily available, chiral ligand entit...
Deprotonation of phenyldibenzo[b,f]tropylidene (8) with LDA/t-BuOK followed by quenching with either...
A class of chiral sulfoxide-olefins were designed and synthesized through concise routes. Their appl...
A series of axially chiral bis-sulfoxide ligands have been efficiently synthesized via oxidative cou...
Synthesis of novel C<sub>2</sub>-symmetric 1,2- 1,3- and 1,4- bis-sulfinamides and their use as effe...
A Class of Benzene Backbone-Based Olefin-Sulfoxide Ligands for Rh-Catalyzed Enantioselective Additio...
Synthesis of novel C-2-symmetric 1,2-1,3- and 1,4-bis-sulfinamides and their use as effective ligand...
Disulfoxides with atropisomeric backbones are introduced as readily available chiral ligands for the...
At last! The addition of bisulfite to olefins, discovered over a century ago, remains the most strai...
An efficient Rh-catalyzed addition of arylboronic acids to N-tosylarylimines has been developed with...
International audienceThe rational use of directed deprotometallation, sulfur oxidation and sulfoxid...
A new family of sulfinamide/sulfoxide derivatives was synthesized as chiral bidentate ligands by ste...
A stereodivergent synthesis using inexpensive reagents, i.e., dibenzazepine and glucose-derived t-Bu...