EGF and IGFBP-1 are candidates for exerting the inhibitory effect of exercise serum on tumor cell growth.

<p>A) Analysis of growth factor content in rest and exercise serum using a growth factor array approach. B) Rest/exercise serum ratio of 42 growth factors and cytokines, analyzed in multiplex. C) ELISA analysis of individual (left panel) and average (right panel) levels of serum EGF in rest and exercise serum, n = 9. D) ELISA analysis of individual (left panel) and average (right panel) levels of serum IGFBP-1 in rest and exercise serum, n = 10. Data is presented as individual levels or mean ± SEM. π denotes a significant (p≤0.05) difference between incubation with rest and exercise serum.