Inhibition of caspase-3 reduced neuronal death following the treatments.

<p>Cells were pre-incubated with DMSO or caspase-3 inhibitor (z-DEVD-FMK) for 2 hours, and then cells were subjected to the indicated treatments for 1 hour. Cell death was detected with trypan blue exclusion assay. * (<i>p</i><0.05) and † (<i>p</i><0.01) denote significant difference from the DMSO groups, respectively. n = 4.