<p><i>Dilp2>dAdipoR-Ri</i> flies were increased in the hemolymph glucose levels (A, B), TAG level (C,D) of larvae and adults compared with those of <i>Dilp2-Gal4</i> and <i>UAS-dAdipoR-Ri</i> control flies. (E) <i>Dilp2>dAdipoR-Ri</i> flies showed the starvation resistance compared with <i>Dilp2-Gal4</i> and <i>UAS-dAdipoR-Ri</i> controls. (F) <i>Dilp2>dAdipoR-Ri</i> flies showed the reduced viability compared with the <i>Dilp2-Gal4 and UAS-dAdipoR-Ri</i> controls on the high fat diet. Data are presented as means ±SEM; *p<0.05, **p<0.01.</p
During the last 20 years, there has been a considerable scientific debate about the possible mechani...
Fruit flies have eight identified Drosophila insulin-like peptides (DILPs) that are involved in the ...
Fruit flies have eight identified Drosophila insulin-like peptides (DILPs) that are involved in the ...
(A) Quantitative PCR shows no difference in DILP2 transcript levels between control flies (DILP2>Luc...
<p>A) Schematic of selection processes for SR and DR flies. Adult outbred flies were placed under de...
The insulin pathway is an anabolic pathway that controls, amongst other things, glucose homeostasis....
<p>Survival of flies placed in activity monitors under starvation conditions. A) Flies from the SR<s...
<p>(a) Compromised Hpo expression elevates larval body size and fat body reporter signal. Third inst...
<p>Macronutrient composition in hemolymph and body of flies kept for 1–12 weeks at 11°C and 10L:14D,...
<p>(A) Circulating trehalose levels in <i>InR</i> or <i>Akt1</i> heterozygous mutants and sibling wi...
<p><b><i>A</i></b><b>,</b> Hemolymph was extracted from flies after fasting, and circulating trehalo...
<p>(A) Larval <i>Dilp2, 3, 5</i> expression levels in <i>Dilp2>dAdipoR-Ri</i> were similar to those ...
<p>(a and b) <i>m2</i> homozygous mutant flies (red) and lansoprazole-treated flies (orange) show in...
<p>Macronutrient composition in hemolymph and body of flies kept for 1–12 weeks at 11°C and 10L:14D,...
During the last 20 years, there has been a considerable scientific debate about the possible mechani...
During the last 20 years, there has been a considerable scientific debate about the possible mechani...
Fruit flies have eight identified Drosophila insulin-like peptides (DILPs) that are involved in the ...
Fruit flies have eight identified Drosophila insulin-like peptides (DILPs) that are involved in the ...
(A) Quantitative PCR shows no difference in DILP2 transcript levels between control flies (DILP2>Luc...
<p>A) Schematic of selection processes for SR and DR flies. Adult outbred flies were placed under de...
The insulin pathway is an anabolic pathway that controls, amongst other things, glucose homeostasis....
<p>Survival of flies placed in activity monitors under starvation conditions. A) Flies from the SR<s...
<p>(a) Compromised Hpo expression elevates larval body size and fat body reporter signal. Third inst...
<p>Macronutrient composition in hemolymph and body of flies kept for 1–12 weeks at 11°C and 10L:14D,...
<p>(A) Circulating trehalose levels in <i>InR</i> or <i>Akt1</i> heterozygous mutants and sibling wi...
<p><b><i>A</i></b><b>,</b> Hemolymph was extracted from flies after fasting, and circulating trehalo...
<p>(A) Larval <i>Dilp2, 3, 5</i> expression levels in <i>Dilp2>dAdipoR-Ri</i> were similar to those ...
<p>(a and b) <i>m2</i> homozygous mutant flies (red) and lansoprazole-treated flies (orange) show in...
<p>Macronutrient composition in hemolymph and body of flies kept for 1–12 weeks at 11°C and 10L:14D,...
During the last 20 years, there has been a considerable scientific debate about the possible mechani...
During the last 20 years, there has been a considerable scientific debate about the possible mechani...
Fruit flies have eight identified Drosophila insulin-like peptides (DILPs) that are involved in the ...
Fruit flies have eight identified Drosophila insulin-like peptides (DILPs) that are involved in the ...