<p>(<b>A</b>–<b>C</b>) Human NSCLC A549 cells were treated with BBR at the indicated doses. At 48 hours after treatment, the AP-2 and hTERT proteins (<b>A</b>) and mRNA (<b>B</b>) were analyzed by Western blotting and RT-PCR, respectively. GAPDH were used as controls for sample loading. The binding of AP-2 to hTERT promoter probe (<b>C</b>) was analyzed by a streptavidin-agarose pulldown assay. (<b>D</b>) A549 cells were transfected with an AP-2 siRNA or an AP-2-expressing vector for 24 hours, and then treated with BBR (100 µM). At 48 hours after treatment, protein expression and cell viability were determined by Western blot and MTT assay, respectively. The percent cell viability in each treatment group was calculated relative to cells tre...
<p>GMCs were treated with S1P, S1P2-siRNA and BBR conditionally under HG condition, and S1P2 recepto...
<p>(<b>A</b>) HGMCs were transfected with control siRNA or LKB1 siRNA for 48 h. Then cells were trea...
<p>HepG2 cells were incubated in the absence or presence of 0.3 mM PA or 0.3 mM PA with 10 μM BBR fo...
<p>(<b>A</b>) Human A549 cells were treated with BBR at the indicated doses. At 48 hours after treat...
<p>A549 cells were treated with BBR at the indicated doses. At 48 hours after treatment, the express...
<p>(<b>A</b>–<b>C</b>) Human A549 and H1299 cells were treated with BBR at the indicated doses. At 4...
<p>A549 and H1299 cells were treated with BBR (20 µM or 100 µM). At 48 hours after treatment, the ap...
<p><b>(A)</b> Western blotting of LC3B in HEK293 cells transfected with or without Htt and treated w...
<p>(A) TBr caused the activation of caspase-8 and its downstream target Bid independent of death rec...
<p>(A) Cells containing control and Bax siRNA were treated with TBr at indicated concentrations for ...
<p>GMCs were treated with BBR (10, 30, 90 µM) and PDTC (100 µM) for 24 h. Protein bands (A) were det...
<p>(<b>A</b>) Cultured primary HGMCs were incubated with BBR (100 µM) for indicated time after starv...
<p>(A) mRNA expressions of endogenous P-gp using real-time PCR assay. (B) Western blotting assay sho...
<p>U251MG cells were knocked down by siRNAs, followed by treatment with conditioned medium collected...
<p>(A) shows the effects of BFRs (TBBPA, HBCD and DBDE) at a range of concentrations, increase caspa...
<p>GMCs were treated with S1P, S1P2-siRNA and BBR conditionally under HG condition, and S1P2 recepto...
<p>(<b>A</b>) HGMCs were transfected with control siRNA or LKB1 siRNA for 48 h. Then cells were trea...
<p>HepG2 cells were incubated in the absence or presence of 0.3 mM PA or 0.3 mM PA with 10 μM BBR fo...
<p>(<b>A</b>) Human A549 cells were treated with BBR at the indicated doses. At 48 hours after treat...
<p>A549 cells were treated with BBR at the indicated doses. At 48 hours after treatment, the express...
<p>(<b>A</b>–<b>C</b>) Human A549 and H1299 cells were treated with BBR at the indicated doses. At 4...
<p>A549 and H1299 cells were treated with BBR (20 µM or 100 µM). At 48 hours after treatment, the ap...
<p><b>(A)</b> Western blotting of LC3B in HEK293 cells transfected with or without Htt and treated w...
<p>(A) TBr caused the activation of caspase-8 and its downstream target Bid independent of death rec...
<p>(A) Cells containing control and Bax siRNA were treated with TBr at indicated concentrations for ...
<p>GMCs were treated with BBR (10, 30, 90 µM) and PDTC (100 µM) for 24 h. Protein bands (A) were det...
<p>(<b>A</b>) Cultured primary HGMCs were incubated with BBR (100 µM) for indicated time after starv...
<p>(A) mRNA expressions of endogenous P-gp using real-time PCR assay. (B) Western blotting assay sho...
<p>U251MG cells were knocked down by siRNAs, followed by treatment with conditioned medium collected...
<p>(A) shows the effects of BFRs (TBBPA, HBCD and DBDE) at a range of concentrations, increase caspa...
<p>GMCs were treated with S1P, S1P2-siRNA and BBR conditionally under HG condition, and S1P2 recepto...
<p>(<b>A</b>) HGMCs were transfected with control siRNA or LKB1 siRNA for 48 h. Then cells were trea...
<p>HepG2 cells were incubated in the absence or presence of 0.3 mM PA or 0.3 mM PA with 10 μM BBR fo...