<p>For comparative reference, the molar concentration of each drug at 1000 µg/mL is indicated. Roundworms were scored daily for motility. Any motility, including motility after prodding, was counted as “alive.” Lack of motility, including a lack of a response after prodding, was counted as “dead.” Data are the combination of three independent trials with ~10 nematodes/trial.</p
<p>Synchronized L1 wild-type larvae were incubated with 0.01 µM of Se(IV) or distilled water as the ...
International audienceIvermectin and moxidectin are the most widely administrated anthelmintic macro...
Soil-transmitted helminths (STHs) are intestinal parasitic nematodes that infect humans, and are tra...
<p>For comparative reference, the molar concentration of each drug at 1000 µg/mL is indicated. Paras...
<p>(<b>A</b>) Synchronized L1 and adult wild-type worms were placed on plates containing the specifi...
Treatment was for 14 days with an additional 14 day follow up without the drug. Flubendazole (0.3 μM...
<p>For comparative reference, the molar concentration of each drug at 1000 µg/mL is indicated. Paras...
<p>(A) WT, (B) ivermectin-resistant mutant DA1316, (C) aldicarb-resistant mutant CB113. L4 nematodes...
Many drugs act very rapidly — they can turn on or off their targets within minutes in a whole animal...
Over 1.5 billion impoverished people world-wide are infected with at least one of three different so...
<p>Locomotion behavior of nematodes was evaluated by endpoints of head thrash and body bend. Exposur...
<p>Synchronized wild-type L1 larvae were incubated in liquid S-basal containing <i>E. coli</i> OP50 ...
BACKGROUND: Caenorhbditis elegans has being vigorously used as a model organism in many research fie...
<p>A) Paralysis assay on lines transformed with cDNA expressing other <i>C. elegans</i> GluCl subuni...
Infections from parasitic nematodes (or roundworms) contribute to a significant disease burden and p...
<p>Synchronized L1 wild-type larvae were incubated with 0.01 µM of Se(IV) or distilled water as the ...
International audienceIvermectin and moxidectin are the most widely administrated anthelmintic macro...
Soil-transmitted helminths (STHs) are intestinal parasitic nematodes that infect humans, and are tra...
<p>For comparative reference, the molar concentration of each drug at 1000 µg/mL is indicated. Paras...
<p>(<b>A</b>) Synchronized L1 and adult wild-type worms were placed on plates containing the specifi...
Treatment was for 14 days with an additional 14 day follow up without the drug. Flubendazole (0.3 μM...
<p>For comparative reference, the molar concentration of each drug at 1000 µg/mL is indicated. Paras...
<p>(A) WT, (B) ivermectin-resistant mutant DA1316, (C) aldicarb-resistant mutant CB113. L4 nematodes...
Many drugs act very rapidly — they can turn on or off their targets within minutes in a whole animal...
Over 1.5 billion impoverished people world-wide are infected with at least one of three different so...
<p>Locomotion behavior of nematodes was evaluated by endpoints of head thrash and body bend. Exposur...
<p>Synchronized wild-type L1 larvae were incubated in liquid S-basal containing <i>E. coli</i> OP50 ...
BACKGROUND: Caenorhbditis elegans has being vigorously used as a model organism in many research fie...
<p>A) Paralysis assay on lines transformed with cDNA expressing other <i>C. elegans</i> GluCl subuni...
Infections from parasitic nematodes (or roundworms) contribute to a significant disease burden and p...
<p>Synchronized L1 wild-type larvae were incubated with 0.01 µM of Se(IV) or distilled water as the ...
International audienceIvermectin and moxidectin are the most widely administrated anthelmintic macro...
Soil-transmitted helminths (STHs) are intestinal parasitic nematodes that infect humans, and are tra...