Plate phenotypes of structure-specific endonuclease mutants.

<p>(A) Brood size. Entire brood sizes were scored for singled hermaphrodites of the indicated genotypes. (B) Embryonic lethality. Total numbers of dead eggs/total number of eggs laid were scored. (C) Larval arrest. Arrested L1–L4 worms/total number of hatched worms were scored. (D) Incidence of males. Total number of adult males/total number of adult worms were scored. ND, not determined due to low N values. B, Bristol and H, Hawaiian. Error bars indicate standard error of the mean. Asterisks indicate statistical difference compared to wild type (*P<0.05, **P<0.01, ***P<0.0001, by the two-tailed Mann-Whitney Test, 95% C.I.). The total N-values and the mean values for the plate phenotypes are summarized in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003586#pgen.1003586.s002" target="_blank">Table S1</a>.