Decreased SOCS3 and increased pSTAT3 in presence of miR-19a.

<p>SOCS3 protein basal levels were reduced in Huh7s transfected with double-stranded miR-19a mimic (A), while pSTAT3 was increased following stimulation with IFN-α (B) and IL-6 (C) for 15min over 24 and 48h. Values below blots represent densitometric analysis of SOCS3 or pSTAT3 relative to γ-tubulin and normalised to MMNC=1(n=3).