Plasma corticosterone and ACTH rhythms are disrupted in Sham-operated forced desynchronized rats.

<p>Plasma corticosterone (A) and ACTH (B) in Sham treated rats on aligned (<i>black</i>) and misaligned (<i>grey</i>) days. Black horizontal bars denote times when lights are off. Illustrations (<i>top</i>) show predicted <i>Per1</i> expression patterns, as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0068793#pone-0068793-g002" target="_blank">Figure 2</a>. Data are means ± SEM and fitted with a sine wave function (see materials and methods). n= 6 rats/group.