EBV-encoded dUTPase induces the secretion of cytokines and chemokine in human DCs.
- Maria Eugenia Ariza (435676)
- Pierre Rivailler (153282)
- Ronald Glaser (203112)
- Min Chen (147733)
- Marshall V. Williams (435677)
Publication date
July 2013
DOIAbstract
<p>EBV-encoded dUTPase (10 µg/ml) differentially induce the secretion of T<sub>H</sub>1, T<sub>H</sub>17 cytokines/chemokines in hDCs following a 24 h treatment, as determined by proteome array. (A) IL-6; (B) CCL20 and IL-23; (C) RANTES; (D) IL12p40, TGF-α and TNF-α; (E) IL-10 and IL-1β. Cytokine/chemokine concentrations represent the average ± SD (picograms per milliliter) from two independent experiments (n of 4). *<i>p</i><0.05.</p
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