Leptin enhances the maturity of fetal lungs in the FGR rat model.

<p>A: The relative alveolus area is presented by the ratio of the alveolar area to the lung area, which was calculated by an image analysis program. <i>^#P</i><0.05 <i>vs</i> PBS-treated FGR group (<i>n</i> = 3). B: The field occupied by alveoli and lung tissue is presented as the tissue density, which was analyzed and calculated by ImagePro Plus image analysis software. <i>^#P</i><0.05 <i>vs</i> PBS-treated FGR group (<i>n</i> = 3). C: Histological examination of HE-stained lung tissue sections of fetal rats on day 21 of gestation showed a difference in pulmonary alveoli and interval (arrow noted) between the FGR group, leptin-treated group and control (×200).