Increased levels of ubiquinol_9/10 in the lumbar spinal cord of symptomatic SOD1^G93A mice.

<p>Endogenous levels of CoQ₉ (A–C) and CoQ₁₀ (D–F) in the lumbar spinal cord of male 16 week-old 129Sv SOD1^WT and SOD1^G93A mice are shown as percentage of the levels measured in age-matched 129Sv non-transgenic mice (absolute values in table S1). Panels A, D show the total CoQs levels, whereas panels B, E and panels C, F show the reduced and oxidized forms, respectively. Each value is mean±SEM of 4–7 mice. * P<0.05, ** P<0.01 compared to SOD1^WT mice; ° P<0.05 compared to 129Sv NTg mice (Student’s T-test).