<p>Lowess curve (thick dash-dot line). Upper limit (99<sup>th</sup> centile healthy control values from our laboratory) (thin dashed line). Normal limit defined by assay (MCT only) (thin dotted line). * p-value for difference between pre-antivenom concentration and peak concentration during the first four hours post-antivenom (Wilcoxon Signed Rank Test).</p
Objective: To determine whether monitoring both steady-state peak and trough serum vancomycin concen...
<p>Plots of venom concentration versus time in five of the eight patients who were not given antiven...
<p>Scatterplot of the pre-antivenom Russell's viper venom concentrations (ng/ml) in the patients wit...
<p>Lowess curve (thick dash-dot line). Upper limit (99<sup>th</sup> centile healthy control values f...
<p>Lowess curve (thick dash-dot line). Upper limit (99<sup>th</sup> centile healthy control values f...
<p>Blood samples were taken before and 10 min after drug administration. The plasma histamine concen...
<p>(The whiskers are the minimum and maximum, the box the interquartile range, and the median line a...
<p>The black lines represent the interpolated median factor concentration time curves and the shaded...
*<p>Calculated from assays conducted in our laboratory on healthy controls.</p>†<p>p<0.001 comparing...
<p>The two regimens with repeat doses are compared to a single dose in Panel C.</p
<p>All curves are normalized with respect to the maximal effect of histamine (100%) at the respectiv...
<p>Dots represent the median serum WFA<sup>+</sup>-M2BP values at each time point, and the error bar...
<p>Distribution of procalcitonin (PCT) level according to clinical response to beta-lactam treatment...
<p>Values represent means ± SEM * p = 0.01, ** p = 0.001 and *** p = 0.001 indicates a significant d...
The effects of several antimicrobial agents are predicted by the ratio of the area under the concent...
Objective: To determine whether monitoring both steady-state peak and trough serum vancomycin concen...
<p>Plots of venom concentration versus time in five of the eight patients who were not given antiven...
<p>Scatterplot of the pre-antivenom Russell's viper venom concentrations (ng/ml) in the patients wit...
<p>Lowess curve (thick dash-dot line). Upper limit (99<sup>th</sup> centile healthy control values f...
<p>Lowess curve (thick dash-dot line). Upper limit (99<sup>th</sup> centile healthy control values f...
<p>Blood samples were taken before and 10 min after drug administration. The plasma histamine concen...
<p>(The whiskers are the minimum and maximum, the box the interquartile range, and the median line a...
<p>The black lines represent the interpolated median factor concentration time curves and the shaded...
*<p>Calculated from assays conducted in our laboratory on healthy controls.</p>†<p>p<0.001 comparing...
<p>The two regimens with repeat doses are compared to a single dose in Panel C.</p
<p>All curves are normalized with respect to the maximal effect of histamine (100%) at the respectiv...
<p>Dots represent the median serum WFA<sup>+</sup>-M2BP values at each time point, and the error bar...
<p>Distribution of procalcitonin (PCT) level according to clinical response to beta-lactam treatment...
<p>Values represent means ± SEM * p = 0.01, ** p = 0.001 and *** p = 0.001 indicates a significant d...
The effects of several antimicrobial agents are predicted by the ratio of the area under the concent...
Objective: To determine whether monitoring both steady-state peak and trough serum vancomycin concen...
<p>Plots of venom concentration versus time in five of the eight patients who were not given antiven...
<p>Scatterplot of the pre-antivenom Russell's viper venom concentrations (ng/ml) in the patients wit...