<p>Histomorphometric data and serum biochemical markers were compared in sham-operated, OVX mice, and OVX+KMUP-1 mice. (<b>A</b>) Tb.N, trabecular number, (<b>B</b>) Tb.Th, trabecular thickness, (<b>C</b>) Tb.Sp, trabecular separation, (<b>D</b>) ALP, serum alkaline phosphatase and (<b>E</b>) osteocalcin. All values are expressed as mean ± S.E.M. <sup>#</sup><i>P</i><0.05 compared with the Sham group;<sup> *</sup><i>P</i><0.05, <sup>**</sup><i>P</i><0.01 compared with the OVX group.</p
<p>Bone histomorphometric analysis of lumbar vertebrae from 12-week-old <i>AhR<sup>RANKΔOc/ΔOc</sup>...
<p>Tg2576 mice (at 1 month old, 5 per group, male) were fed with drinking water containing with vehi...
<p>(A) Von Kossa/van Gieson staining of non-decalcified vertebral body sections from 24 weeks old fe...
<p>(<b>A</b>) OVX mice were sacrificed after 30 days of KMUP-1 treatment. Images of the longitudinal...
<p>(A) Tibial bone sections from sham and OVX-treated mice were stained and representative figures a...
BACKGROUND: KMUP-1 is a xanthine derivative with inhibitory activities on the phosphodiesterase (PDE...
KMUP-1 is a xanthine derivative with inhibitory activities on the phosphodiesterase (PDE) 3,4 and 5 ...
KMUP-1 is a xanthine derivative with inhibitory activities on the phosphodiesterase (PDE) 3,4 and 5 ...
<div><p>Background</p><p>KMUP-1 is a xanthine derivative with inhibitory activities on the phosphodi...
<p>Female ICR mice were ovariectomized (OVX) or given a sham operation (Sham). OVX mice were orally ...
<p>OVX mice were subcutaneously injected with vehicle, 15d-PGJ<sub>2</sub>, or E2 (10 μg/kg) for 10 ...
<p>(A) TRAP staining reveals increased osteoclasts in trabecular bone at the proximal tibia from KO ...
<p>(A-B) Measurements of serum levels of osteocalcin (A) and PYD (B) in 4-month-old WT and Tg2576 mi...
<p>(A) WT, MKK3−/− and MKK6−/− mice were subjected to ovariectomy and bone loss was calculated using...
Background: KMUP-1 is a xanthine derivative with inhibitory activities on the phosphodiesterase (PDE...
<p>Bone histomorphometric analysis of lumbar vertebrae from 12-week-old <i>AhR<sup>RANKΔOc/ΔOc</sup>...
<p>Tg2576 mice (at 1 month old, 5 per group, male) were fed with drinking water containing with vehi...
<p>(A) Von Kossa/van Gieson staining of non-decalcified vertebral body sections from 24 weeks old fe...
<p>(<b>A</b>) OVX mice were sacrificed after 30 days of KMUP-1 treatment. Images of the longitudinal...
<p>(A) Tibial bone sections from sham and OVX-treated mice were stained and representative figures a...
BACKGROUND: KMUP-1 is a xanthine derivative with inhibitory activities on the phosphodiesterase (PDE...
KMUP-1 is a xanthine derivative with inhibitory activities on the phosphodiesterase (PDE) 3,4 and 5 ...
KMUP-1 is a xanthine derivative with inhibitory activities on the phosphodiesterase (PDE) 3,4 and 5 ...
<div><p>Background</p><p>KMUP-1 is a xanthine derivative with inhibitory activities on the phosphodi...
<p>Female ICR mice were ovariectomized (OVX) or given a sham operation (Sham). OVX mice were orally ...
<p>OVX mice were subcutaneously injected with vehicle, 15d-PGJ<sub>2</sub>, or E2 (10 μg/kg) for 10 ...
<p>(A) TRAP staining reveals increased osteoclasts in trabecular bone at the proximal tibia from KO ...
<p>(A-B) Measurements of serum levels of osteocalcin (A) and PYD (B) in 4-month-old WT and Tg2576 mi...
<p>(A) WT, MKK3−/− and MKK6−/− mice were subjected to ovariectomy and bone loss was calculated using...
Background: KMUP-1 is a xanthine derivative with inhibitory activities on the phosphodiesterase (PDE...
<p>Bone histomorphometric analysis of lumbar vertebrae from 12-week-old <i>AhR<sup>RANKΔOc/ΔOc</sup>...
<p>Tg2576 mice (at 1 month old, 5 per group, male) were fed with drinking water containing with vehi...
<p>(A) Von Kossa/van Gieson staining of non-decalcified vertebral body sections from 24 weeks old fe...