<p>Histological sections of liver stained with HE from TLR9<sup>−/−</sup> C57BL/6 mice (A to F) and WT C57BL/6 mice (G and H) intravenously infected with 1×10<sup>6</sup> wild-type <i>P. brasiliensis</i> ATCC 60855 yeast cells grown to the exponential phase. Magnification: ×10 (A, B, D, E, G and H); ×40 (F) and ×60 (C). Squares represent either tissue with inflammatory infiltrates (A and B) or with necrotic areas (D and E). Figures C and F represent magnifications of B and E, respectively. <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0002317#s3" target="_blank">Results</a> are from one representative experiment of two independent experiments. White bars represent 200 µm.</p
<p>A, D, G, J. Untreated and uninfected control mice. B, E, H, K. Untreated infected mice. C, F, I, ...
<p>IgG-treated (A, B) and anti-CD25-treated (C, D) A/J mice showed equivalent diffuse inflammatory r...
<p>For all the experimental groups, liver sections were prepared from the liver retrieved at 72 hpi,...
<p>BALB/c mice were euthanized 90 days after treatment. The lungs, spleens, and livers were excised,...
<p>BALB/c mice were euthanized 40 days after treatment. The lungs, spleens, and livers were excised,...
<p>Photomicrographs of lungs, livers and spleens from WT (A to F) and IL-10<sup>−/−</sup> (G to L) m...
<p>Levels of cytokines detected upon intravenous infection of WT and TLR9<sup>−/−</sup> C57BL/6 mice...
<p>Photomicrographs of lungs from 1MT treated and untreated A/J (<b>A</b>) and B10.A (<b>B</b>) mice...
<p>Representative survival curves of an experimental intravenous infection carried out in WT and TLR...
<p>Evaluation of the fungal burdens in lungs and liver of male (grey bars) and female (open bars) mi...
<p>Male BALB/c mice (n = 5 mice/group for each analyses per experiment replicate) were inoculated wi...
<p>Groups (n = 6) of A/J and B10.A mice were infected i.t. with 1×10<sup>6</sup> yeasts cells of <i>...
<p>Cytokine levels for TNF-α (A), IFN-γ (B), IL-1β (C), IL-6 (D), CXCL-1/KC (E) and CXCL-2/MIP-2 (F)...
<p>(A) Histopathological analysis of hepatic tissue sections with hematoxylin and eosin staining fro...
<p>Tissue sections from control and infected animals were stained with H&E (panels A and E), a modif...
<p>A, D, G, J. Untreated and uninfected control mice. B, E, H, K. Untreated infected mice. C, F, I, ...
<p>IgG-treated (A, B) and anti-CD25-treated (C, D) A/J mice showed equivalent diffuse inflammatory r...
<p>For all the experimental groups, liver sections were prepared from the liver retrieved at 72 hpi,...
<p>BALB/c mice were euthanized 90 days after treatment. The lungs, spleens, and livers were excised,...
<p>BALB/c mice were euthanized 40 days after treatment. The lungs, spleens, and livers were excised,...
<p>Photomicrographs of lungs, livers and spleens from WT (A to F) and IL-10<sup>−/−</sup> (G to L) m...
<p>Levels of cytokines detected upon intravenous infection of WT and TLR9<sup>−/−</sup> C57BL/6 mice...
<p>Photomicrographs of lungs from 1MT treated and untreated A/J (<b>A</b>) and B10.A (<b>B</b>) mice...
<p>Representative survival curves of an experimental intravenous infection carried out in WT and TLR...
<p>Evaluation of the fungal burdens in lungs and liver of male (grey bars) and female (open bars) mi...
<p>Male BALB/c mice (n = 5 mice/group for each analyses per experiment replicate) were inoculated wi...
<p>Groups (n = 6) of A/J and B10.A mice were infected i.t. with 1×10<sup>6</sup> yeasts cells of <i>...
<p>Cytokine levels for TNF-α (A), IFN-γ (B), IL-1β (C), IL-6 (D), CXCL-1/KC (E) and CXCL-2/MIP-2 (F)...
<p>(A) Histopathological analysis of hepatic tissue sections with hematoxylin and eosin staining fro...
<p>Tissue sections from control and infected animals were stained with H&E (panels A and E), a modif...
<p>A, D, G, J. Untreated and uninfected control mice. B, E, H, K. Untreated infected mice. C, F, I, ...
<p>IgG-treated (A, B) and anti-CD25-treated (C, D) A/J mice showed equivalent diffuse inflammatory r...
<p>For all the experimental groups, liver sections were prepared from the liver retrieved at 72 hpi,...