Immunofluorescence microscopy of phage clones from round 2 of panning.

<p><i>(A)</i> PSMA (100 nM) inhibited the binding of Clone 1 (ARLSHRPSYLLVCA) and Clone 2 (GTAVASRVYSLHSLM) to PSMA-postive LNCaP cells, indicating that the uptake was receptor specific (scale is 30 µm). <i>(B)</i> Immunofluorescence microscopy of phage clones from round 2 of panning indicate that the panning process is biased toward PSMA binding (“*” denotes <i>P<0.05</i>).