Celecoxib induced apoptosis in CGCCA cells.

<p>CGCCA cells were treated with the indicated concentrations of celecoxib for 2 days. (A) TUNNEL assay was used to identify apoptotic cells under different concentrations of celecoxib. Cell morphology and the nuclei were revealed by Harris modified hematoxylin solution counter-staining. The arrows indicated cells positive (+) for TUNNEL assay. The examples of positive (+) and negative (–) cells for TUNNEL assay were shown in the right lower corner panel (B) The apoptotic index of CGCCA cells treated with different concentrations of celecoxib. Each value is a mean ± SD of 3 to 5 determinations. *p<0.05, **p<0.001 (versus control).