<p>(A) Analysis of surface phenotypic markers (CD3, CD8) of T cells. T lymphocytes (n = 20) co-cultured with SF-NPC or UMC-NPC were labeled with different fluorescence-conjugated antibodies, dividing into two obvious cell groups (CD3+CD8− T cells and CD3+CD8+ T cells) monitored by flow cytometry analysis. (B and C) Analysis of perforin and granzyme B expression in T cells. Differences between groups were analyzed by paired-samples <i>t</i>-tests (<i>P</i><<i>0.05</i>).</p
Granzymes (Gzm) are a group of serine proteases which are stored in the granules of cytotoxic lympho...
Cytolytic enzymes (CEs) are critical mediators of anti-viral and -tumor immunity; however, as a numb...
<p>CFSE-labeled PBMC from a healthy individual were cultured for 7 days with allogeneic splenocyte-d...
<p>(A) Analysis of surface phenotypic markers (CD3, CD8, CD56) of T cells and NK cells. PBMCs (n = 2...
<p>CD8 T-cell responses were analyzed within six CD8 T-cell subsets defined by 2B4, CD160 and/or PD-...
<p>(<b>A</b>) Enhanced production of perforin and granzyme B from CD8<sup>+</sup> T cells cultured w...
<p>Lymphocytes isolated from peripheral blood (PBMC) and sentinel node (SN) were cultured for seven ...
Freshly isolated PBMCs and digested tumor tissues from 10 paired patients were stained by flow cytom...
<p>Intracellular expression of perforin, granzyme and granulysin in control or <i>Mtb-</i>stimulated...
<p>(<b>A</b>) The expression of granzyme B and perforin in CD8<sup>+</sup> T cells of different tiss...
<p>CD8<sup>+</sup> T cells sorted from sentinel node (SN) were cultured in Tc1 conditions <i>in vitr...
Here we show that the genes for perforin, the three major T cell granzymes (A-C) and IFN-γ are diffe...
Perforin and granzymes are considered to be instrumental in cell-mediated cytolysis by cytotoxic T c...
Cytotoxic T lymphocytes (CTLs) and natu-ral killer (NK) cells use the perforin/ granzyme pathway as ...
<p>A2-ILI tetramer+ CD8 T cells were co-stained with anti-CD45RA, CCR7, CD27, CD28, granzyme B, gran...
Granzymes (Gzm) are a group of serine proteases which are stored in the granules of cytotoxic lympho...
Cytolytic enzymes (CEs) are critical mediators of anti-viral and -tumor immunity; however, as a numb...
<p>CFSE-labeled PBMC from a healthy individual were cultured for 7 days with allogeneic splenocyte-d...
<p>(A) Analysis of surface phenotypic markers (CD3, CD8, CD56) of T cells and NK cells. PBMCs (n = 2...
<p>CD8 T-cell responses were analyzed within six CD8 T-cell subsets defined by 2B4, CD160 and/or PD-...
<p>(<b>A</b>) Enhanced production of perforin and granzyme B from CD8<sup>+</sup> T cells cultured w...
<p>Lymphocytes isolated from peripheral blood (PBMC) and sentinel node (SN) were cultured for seven ...
Freshly isolated PBMCs and digested tumor tissues from 10 paired patients were stained by flow cytom...
<p>Intracellular expression of perforin, granzyme and granulysin in control or <i>Mtb-</i>stimulated...
<p>(<b>A</b>) The expression of granzyme B and perforin in CD8<sup>+</sup> T cells of different tiss...
<p>CD8<sup>+</sup> T cells sorted from sentinel node (SN) were cultured in Tc1 conditions <i>in vitr...
Here we show that the genes for perforin, the three major T cell granzymes (A-C) and IFN-γ are diffe...
Perforin and granzymes are considered to be instrumental in cell-mediated cytolysis by cytotoxic T c...
Cytotoxic T lymphocytes (CTLs) and natu-ral killer (NK) cells use the perforin/ granzyme pathway as ...
<p>A2-ILI tetramer+ CD8 T cells were co-stained with anti-CD45RA, CCR7, CD27, CD28, granzyme B, gran...
Granzymes (Gzm) are a group of serine proteases which are stored in the granules of cytotoxic lympho...
Cytolytic enzymes (CEs) are critical mediators of anti-viral and -tumor immunity; however, as a numb...
<p>CFSE-labeled PBMC from a healthy individual were cultured for 7 days with allogeneic splenocyte-d...