Enhanced BMP signaling fails to alter osteoblastogenesis by GCT stromal cells.
- Matthew R. Steensma (437868)
- Wakenda K. Tyler (437869)
- Allison G. Shaber (437870)
- Steven R. Goldring (437871)
- F. Patrick Ross (437872)
- Bart O. Williams (177042)
- John H. Healey (351696)
- P. Edward Purdue (437873)
Publication date
July 2013
DOIAbstract
<p>(A) GAPDH-normalized expression (qPCR) of osteocalcin mRNA levels after 12 days of growth in MEM-α in the absence or presence of recombinant human BMP2. (B) Western blot analysis of phsopho-Smad 1/5 at 1 and 3 hours after treatment of cultures with vehicle or BMP2, indicating up-regulation of BMP signaling.</p
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