Reduced lymphoid differentiation ratio and increased myeloid differentiation ratio of WT WBMCs in CL recipients.

<p>1×10⁶ CD45.1 WBMCs were transplanted into lethally irradiated (9.5 Gy) WT or CL mice. (<b>A</b>) Donor cell percentage in PB was analyzed by flow cytometry every 4 weeks. Data shown are mean ± SEM (n = 7–10). (<b>B–D</b>) The ratio of T lymphocyte, B lymphocyte and myeloid cell of donor cells in PB was analyzed by flow cytometry every 4 weeks. Data shown are mean ± SEM (*P<0.05, **P<0.01, ***P<0.001, n = 7–10). (<b>E</b>) The CD45.1 donor cell percentage in BM by flow cytometry at 24 weeks after transplantation. Data shown are mean ± SEM (n = 7–10). (<b>F</b>) T lymphocyte, B lymphocyte, myeloid cell and granulocyte percentage of CD45.1 donor cells in BM, analyzed by flow cytometry at 24 weeks after transplantation Data shown are mean ± SEM (*P<0.05, **P<0.01, n = 7–10).