In A, the inverse relation between <i>Q</i>_max and <i>R_p</i> is noted after pooling the data of all the groups (<i>Q</i>_max = 47.7300−0.2064× <i>R_p</i> and <i>r</i> = 0.2909; <i>p</i><0.005).

<p>However, the significant inverse linear correlation between the two parameters is predominantly derived from the data of the DM and DM+OXF groups (<i>Q</i>_max = 50.9368−0.3126× <i>R_p</i> and <i>r</i> = 0.4390; <i>p</i><0.05 in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0069977#pone-0069977-g004" target="_blank">Figure 4B</a>). NC, normal controls; NC+ALC, NC treated with ALC; NC+OXF, NC treated with OXF; DM, STZ-induced diabetic rats; DM+ALC, DM treated with ALC; DM+OXF, DM treated with OXF; ALC, acetyl-L-carnitine; OXF, oxfenicine; <i>Q</i>_max, the theoretical maximum flow; <i>R_p</i>, the total peripheral resistance.