Reduced NAC1 expression is associated with alterations in chondrocytic expression of <i>matrilin-3</i> and <i>matrilin-4</i>.

<p>Quantitative real-time PCR analysis performed on cultured costal chondrocytes derived from Nacc1^+/+ (wild type) and Nacc1^-/- (knockout) mouse pups at postnatal day 1 (P1) to measure the relative expression levels of the different matrilin (MATN) proteins. Only MATN3 and MATN4 are expressed at a significantly different level (** denotes p < 0.01) between the two genotypes.