Reduced NAC1 expression is associated with altered specification of cartilage primordia for vertebral patterning.
- Kai Lee Yap (438070)
- Polina Sysa-Shah (144392)
- Brad Bolon (30121)
- Ren-Chin Wu (167828)
- Min Gao (87060)
- Alice L. Herlinger (438071)
- Fengying Wang (438072)
- Francesco Faiola (438073)
- David Huso (438074)
- Kathleen Gabrielson (144398)
- Tian-Li Wang (49187)
- Jianlong Wang (438075)
- Ie-Ming Shih (49189)
Publication date
July 2013
DOIAbstract
<p>Comparison of representative Alcian blue-stained, whole mount mouse embryos at embryonic day 15 (E15) reveals the typical vertebral formulas related to the Nacc1<sup>+/+</sup> (wild type, formula T13/L6), Nacc1<sup>+/-</sup> (heterozygous, formula T13/L5), and Nacc1<sup>-/-</sup> (knockout, formula T12/L6) genotypes. The numbers denote the number of vertebrae in the thoracic (T, top row) and lumbar (L, bottom row) regions of the vertebral column.</p
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