Sample-size estimates based on delta NPD*.

Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial - the development of the DELTA guidance

Sones, William
Julious, Steven A
Rothwell, Joanne C
Ramsay, Craig Robert
Hampson, Lisa V
Emsley, Richard
Walters, Stephen J
Hewitt, Catherine
Bland, Martin
Fergusson, Dean A
Berlin, Jesse A
Altman, Doug
Vale, Luke David
Cook, Jonathan Alistair

October 2018

BACKGROUND: A key step in the design of a randomised controlled trial is the estimation of the numbe...

DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial Suzie Cro

Cook, J.A.
Julious, S.A.
Sones, W.
Hampson, L.V.
Hewitt, C.
Berlin, J.A.
Ashby, D.
Emsley, R.
Fergusson, D.A.
Walters, S.J.
Wilson, E.C.F.
Maclennan, G.
Stallard, N.
Rothwell, J.C.
Bland, M.
Brown, L.
Ramsay, C.R.
Cook, A.
Armstrong, D.
Altman, D.
Vale, L.D.

November 2018

Background: A key step in the design of a RCT is the estimation of the number of participants needed...

Effect size estimates as percentage change in NT-proBNP and 95% confidence intervals (95%-CI) using sex-specific income quartiles (4th quartile as reference) in the main analysis population and stratified by sex.

Marina Rudman (11307354)
Mirjam Frank (4386298)
Carina Emmel (11307357)
Emanuel Matusch (11307360)
Kaffer Kara (11307363)
Amir Abbas Mahabadi (3216606)
Raimund Erbel (49439)
Karl-Heinz Jöckel (15194)
Nico Dragano (49434)
Börge Schmidt (4386301)

August 2021

Effect size estimates as percentage change in NT-proBNP and 95% confidence intervals (95%-CI) using ...

Sample-size estimates based on average basal PD (ENaC)*.

Steven M. Rowe (154935)
Bo Liu (127343)
Aubrey Hill (438286)
Heather Hathorne (438287)
Morty Cohen (438288)
John R. Beamer (438289)
Frank J. Accurso (236320)
Qunming Dong (438290)
Claudia L. Ordoñez (438291)
Anne J. Stone (438292)
Eric R. Olson (438293)
John P. Clancy (438294)

July 2013

Sample-size estimates based on average basal PD (ENaC)<a href="http://www.plosone.org/articl...

Sample-size estimates based on zero Cl− plus isoproterenol (CFTR) response*.

Steven M. Rowe (154935)
Bo Liu (127343)
Aubrey Hill (438286)
Heather Hathorne (438287)
Morty Cohen (438288)
John R. Beamer (438289)
Frank J. Accurso (236320)
Qunming Dong (438290)
Claudia L. Ordoñez (438291)
Anne J. Stone (438292)
Eric R. Olson (438293)
John P. Clancy (438294)

July 2013

Sample-size estimates based on zero Cl− plus isoproterenol (CFTR) response<a href...

Differences in sample size for a non-inferiority trial when calculated using rates or allowing for survival analysis.

Piero Olliaro (35337)
Michel Vaillant (39101)
Byron Arana (392805)
Max Grogl (4762899)
Farrokh Modabber (35109)
Alan Magill (392806)
Olivier Lapujade (217600)
Pierre Buffet (82569)
Jorge Alvar (253327)

March 2013

Sample size expressed as % underestimation when calculated using rates vs. survival analysis; del...

Determination of sample size

Nyi Nyi Naing

July 2003

There is a particular importance of determining a basic minimum required `n' size of the sample to r...

Samples size calculation (N per group) for non-inferiority trials.

Piero Olliaro (35337)
Michel Vaillant (39101)
Byron Arana (392805)
Max Grogl (4762899)
Farrokh Modabber (35109)
Alan Magill (392806)
Olivier Lapujade (217600)
Pierre Buffet (82569)
Jorge Alvar (253327)

March 2013

Success rate ranging 60–90%; exclusions ranging 0–25%; non-inferiority margin (delta) 6%, 8% and ...

DELTA 2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

Cook, J.A.
Julious, S.A.
Sones, W.
Hampson, L.V.
Hewitt, C.
Berlin, J.A.
Ashby, D.
Emsley, R.
Fergusson, D.A.
Walters, S.J.
Wilson, E.C.F.
MacLennan, G.
Stallard, N.
Rothwell, J.C.
Bland, M.
Brown, L.
Ramsay, C.R.
Cook, A.
Armstrong, D.
Altman, D.
Vale, L.D.

November 2018

Randomised controlled trials are considered to be the best method to assess comparative clinical eff...

Sample sizes (n) for objective 1 (time series analysis of spatial distribution) and objective 2 (relative importance of predictor variables on spatial distribution).

Charles F. Adams (5146427)
Larry A. Alade (5146436)
Christopher M. Legault (5146433)
Loretta O’Brien (5146430)
Michael C. Palmer (5146439)
Katherine A. Sosebee (5146445)
Michele L. Traver (5146442)

April 2018

Sample sizes (n) for objective 1 (time series analysis of spatial distribution) and object...

DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial.

Cook, Jonathan A
Julious, Steven A
Sones, William
Hampson, Lisa V
Hewitt, Catherine
Berlin, Jesse A
Ashby, Deborah
Emsley, Richard
Fergusson, Dean A
Walters, Stephen J
Wilson, Ed
MacLennan, Graeme
Stallard, Nigel
Rothwell, Joanne C
Bland, Martin
Brown, Louise
Ramsay, Craig R
Cook, Andrew
Armstrong, David
Altman, Doug
Vale, Luke D

November 2018

The randomised controlled trial (RCT) is considered the gold standard to assess comparative clinical...

Tutorial in biostatistics: sample sizes for parallel group clinical trials with binary data

Julious, S.A.
Campbell, M.J.

October 2012

This article gives an overview of sample size calculations for a single response and a comparison of...

DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

Cook, J
Julious, SA
Sones, WR
Hampson, LV
Hewitt, C
Berlin, JA
Ashby, D
Emsley, R
Fergusson, DA
Walters, SJ
Wilson, ECF
Maclennan, G
Stallard, N
Rothwell, JC
Bland, M
Brown, L
Ramsay, CR
Cook, A
Armstrong, D
Altman, D
Vale, LD

November 2018

Background This article on choosing the target difference for a randomised controlled trial (RCT) an...

Sample sizes for different clinical outcomes based on input and prediction score.

Hongyi Dammu (14341487)
Thomas Ren (14341490)
Tim Q. Duong (9179067)

January 2023

Sample sizes for different clinical outcomes based on input and prediction score.</p

Why sample size estimates?

Weber, Ellen J
Hoo, Zhe Hui

December 2018

Sample size estimates are critical to the planning and interpretation of clinical studies, whether t...

Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial - the development of the DELTA guidance

Sones, William
Julious, Steven A
Rothwell, Joanne C
Ramsay, Craig Robert
Hampson, Lisa V
Emsley, Richard
Walters, Stephen J
Hewitt, Catherine
Bland, Martin
Fergusson, Dean A
Berlin, Jesse A
Altman, Doug
Vale, Luke David
Cook, Jonathan Alistair

October 2018

BACKGROUND: A key step in the design of a randomised controlled trial is the estimation of the numbe...

DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial Suzie Cro

Cook, J.A.
Julious, S.A.
Sones, W.
Hampson, L.V.
Hewitt, C.
Berlin, J.A.
Ashby, D.
Emsley, R.
Fergusson, D.A.
Walters, S.J.
Wilson, E.C.F.
Maclennan, G.
Stallard, N.
Rothwell, J.C.
Bland, M.
Brown, L.
Ramsay, C.R.
Cook, A.
Armstrong, D.
Altman, D.
Vale, L.D.

November 2018

Background: A key step in the design of a RCT is the estimation of the number of participants needed...

Effect size estimates as percentage change in NT-proBNP and 95% confidence intervals (95%-CI) using sex-specific income quartiles (4th quartile as reference) in the main analysis population and stratified by sex.

Marina Rudman (11307354)
Mirjam Frank (4386298)
Carina Emmel (11307357)
Emanuel Matusch (11307360)
Kaffer Kara (11307363)
Amir Abbas Mahabadi (3216606)
Raimund Erbel (49439)
Karl-Heinz Jöckel (15194)
Nico Dragano (49434)
Börge Schmidt (4386301)

August 2021

Effect size estimates as percentage change in NT-proBNP and 95% confidence intervals (95%-CI) using ...

Sample-size estimates based on average basal PD (ENaC)*.

Steven M. Rowe (154935)
Bo Liu (127343)
Aubrey Hill (438286)
Heather Hathorne (438287)
Morty Cohen (438288)
John R. Beamer (438289)
Frank J. Accurso (236320)
Qunming Dong (438290)
Claudia L. Ordoñez (438291)
Anne J. Stone (438292)
Eric R. Olson (438293)
John P. Clancy (438294)

July 2013

Sample-size estimates based on average basal PD (ENaC)<a href="http://www.plosone.org/articl...

Sample-size estimates based on zero Cl− plus isoproterenol (CFTR) response*.

Steven M. Rowe (154935)
Bo Liu (127343)
Aubrey Hill (438286)
Heather Hathorne (438287)
Morty Cohen (438288)
John R. Beamer (438289)
Frank J. Accurso (236320)
Qunming Dong (438290)
Claudia L. Ordoñez (438291)
Anne J. Stone (438292)
Eric R. Olson (438293)
John P. Clancy (438294)

July 2013

Sample-size estimates based on zero Cl− plus isoproterenol (CFTR) response<a href...

Differences in sample size for a non-inferiority trial when calculated using rates or allowing for survival analysis.

Piero Olliaro (35337)
Michel Vaillant (39101)
Byron Arana (392805)
Max Grogl (4762899)
Farrokh Modabber (35109)
Alan Magill (392806)
Olivier Lapujade (217600)
Pierre Buffet (82569)
Jorge Alvar (253327)

March 2013

Sample size expressed as % underestimation when calculated using rates vs. survival analysis; del...

Determination of sample size

Nyi Nyi Naing

July 2003

There is a particular importance of determining a basic minimum required `n' size of the sample to r...

Samples size calculation (N per group) for non-inferiority trials.

Piero Olliaro (35337)
Michel Vaillant (39101)
Byron Arana (392805)
Max Grogl (4762899)
Farrokh Modabber (35109)
Alan Magill (392806)
Olivier Lapujade (217600)
Pierre Buffet (82569)
Jorge Alvar (253327)

March 2013

Success rate ranging 60–90%; exclusions ranging 0–25%; non-inferiority margin (delta) 6%, 8% and ...

DELTA 2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

Cook, J.A.
Julious, S.A.
Sones, W.
Hampson, L.V.
Hewitt, C.
Berlin, J.A.
Ashby, D.
Emsley, R.
Fergusson, D.A.
Walters, S.J.
Wilson, E.C.F.
MacLennan, G.
Stallard, N.
Rothwell, J.C.
Bland, M.
Brown, L.
Ramsay, C.R.
Cook, A.
Armstrong, D.
Altman, D.
Vale, L.D.

November 2018

Randomised controlled trials are considered to be the best method to assess comparative clinical eff...

Sample sizes (n) for objective 1 (time series analysis of spatial distribution) and objective 2 (relative importance of predictor variables on spatial distribution).

Charles F. Adams (5146427)
Larry A. Alade (5146436)
Christopher M. Legault (5146433)
Loretta O’Brien (5146430)
Michael C. Palmer (5146439)
Katherine A. Sosebee (5146445)
Michele L. Traver (5146442)

April 2018

Sample sizes (n) for objective 1 (time series analysis of spatial distribution) and object...

DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial.

Cook, Jonathan A
Julious, Steven A
Sones, William
Hampson, Lisa V
Hewitt, Catherine
Berlin, Jesse A
Ashby, Deborah
Emsley, Richard
Fergusson, Dean A
Walters, Stephen J
Wilson, Ed
MacLennan, Graeme
Stallard, Nigel
Rothwell, Joanne C
Bland, Martin
Brown, Louise
Ramsay, Craig R
Cook, Andrew
Armstrong, David
Altman, Doug
Vale, Luke D

November 2018

The randomised controlled trial (RCT) is considered the gold standard to assess comparative clinical...

Tutorial in biostatistics: sample sizes for parallel group clinical trials with binary data

Julious, S.A.
Campbell, M.J.

October 2012

This article gives an overview of sample size calculations for a single response and a comparison of...

DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial

Cook, J
Julious, SA
Sones, WR
Hampson, LV
Hewitt, C
Berlin, JA
Ashby, D
Emsley, R
Fergusson, DA
Walters, SJ
Wilson, ECF
Maclennan, G
Stallard, N
Rothwell, JC
Bland, M
Brown, L
Ramsay, CR
Cook, A
Armstrong, D
Altman, D
Vale, LD

November 2018

Background This article on choosing the target difference for a randomised controlled trial (RCT) an...

Sample sizes for different clinical outcomes based on input and prediction score.

Hongyi Dammu (14341487)
Thomas Ren (14341490)
Tim Q. Duong (9179067)

January 2023

Sample sizes for different clinical outcomes based on input and prediction score.</p

Why sample size estimates?

Weber, Ellen J
Hoo, Zhe Hui

December 2018

Sample size estimates are critical to the planning and interpretation of clinical studies, whether t...

Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial - the development of the DELTA guidance

Sones, William
Julious, Steven A
Rothwell, Joanne C
Ramsay, Craig Robert
Hampson, Lisa V
Emsley, Richard
Walters, Stephen J
Hewitt, Catherine
Bland, Martin
Fergusson, Dean A
Berlin, Jesse A
Altman, Doug
Vale, Luke David
Cook, Jonathan Alistair

October 2018

BACKGROUND: A key step in the design of a randomised controlled trial is the estimation of the numbe...

DELTA2 guidance on choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial Suzie Cro

Cook, J.A.
Julious, S.A.
Sones, W.
Hampson, L.V.
Hewitt, C.
Berlin, J.A.
Ashby, D.
Emsley, R.
Fergusson, D.A.
Walters, S.J.
Wilson, E.C.F.
Maclennan, G.
Stallard, N.
Rothwell, J.C.
Bland, M.
Brown, L.
Ramsay, C.R.
Cook, A.
Armstrong, D.
Altman, D.
Vale, L.D.

November 2018

Background: A key step in the design of a RCT is the estimation of the number of participants needed...

Effect size estimates as percentage change in NT-proBNP and 95% confidence intervals (95%-CI) using sex-specific income quartiles (4th quartile as reference) in the main analysis population and stratified by sex.

Marina Rudman (11307354)
Mirjam Frank (4386298)
Carina Emmel (11307357)
Emanuel Matusch (11307360)
Kaffer Kara (11307363)
Amir Abbas Mahabadi (3216606)
Raimund Erbel (49439)
Karl-Heinz Jöckel (15194)
Nico Dragano (49434)
Börge Schmidt (4386301)

August 2021

Effect size estimates as percentage change in NT-proBNP and 95% confidence intervals (95%-CI) using ...

Sample-size estimates based on delta NPD<sup>*</sup>.

Abstract

Extracted data

Sample-size estimates based on delta NPD<sup>*</sup>.

Abstract

Extracted data

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