Role of TGF-β in HGF Proliferation after CsA Treatment.

<p>(A) CsA enhanced cell proliferation by MTS assay and RT-PCR analysis of PCNA. (B) CsA increased TGF-β mRNA and protein expressions, examined by RT-PCR (24 h) and Western blotting (48 h). (C) TGF-β enhanced cell proliferation and (D) inhibition of TGF-β mitigated the CsA-enhanced cell proliferation. Experiments were repeated 3 times. Data are expressed as mean and SD; *significantly different from the control group at <i>p</i><0.05 by Student’s <i>t</i>-test or one-way ANOVA; and a–b, subsets obtained after <i>post hoc</i> analysis.).