Fluorescence emission spectra of drug-tRNA systems in 10 mM Tris-HCl buffer pH 7.4 at 25°C for A) DOX-tRNA: (a) free DOX (20 μM), (b-k) with DOX-tRNA complexes at 5, 10, 15, 20, 30, 40, 50, 60, 70 and 80 μM; B) FDOX-tRNA: (a) free FDOX (20 μM), (b-gj) with FDOX-tRNA complexes at 5, 10, 20, 30, 40 and 60 μM. Inset: <i>F</i><sub>0</sub> / (<i>F</i><sub>0</sub> – <i>F</i>) vs 1 / [tRNA] for A' (DOX-tRNA) and B' (FDOX-tRNA).
- Daniel Agudelo (310354)
- Philippe Bourassa (178275)
- Marc Beauregard (438834)
- Gervais Bérubé (310357)
- Heidar-Ali Tajmir-Riahi (178288)
Publication date
July 2013
DOIAbstract
<p>Fluorescence emission spectra of drug-tRNA systems in 10 mM Tris-HCl buffer pH 7.4 at 25°C for A) DOX-tRNA: (a) free DOX (20 μM), (b-k) with DOX-tRNA complexes at 5, 10, 15, 20, 30, 40, 50, 60, 70 and 80 μM; B) FDOX-tRNA: (a) free FDOX (20 μM), (b-gj) with FDOX-tRNA complexes at 5, 10, 20, 30, 40 and 60 μM. Inset: <i>F</i><sub>0</sub> / (<i>F</i><sub>0</sub> – <i>F</i>) vs 1 / [tRNA] for A' (DOX-tRNA) and B' (FDOX-tRNA).</p
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