The receiver-operating characteristic (ROC) plots for the miRNA signature.

<p>The true positive rate (TPR) is plotted as a function of false positive rate (FPR) for the 7 miRNAs individually (upper panel) and for selected combination of them (lower panel). We used the linear discriminant analysis (LDA) to build a model on the training data (11 AD and 17 controls) to predict the AD status of 37 patients (20 AD and 17 controls). These miRNA combinations are all characterized with high area under the curve (AUC) values (>0.93).