<p><b>A.</b> Average waveforms of hourly sleep in WT, Q175 Het and Hom mice at 9 months (top) and 12 months of age (bottom). <b>B.</b> Amount of time spent in sleep in day is selectively decreased compared to night-time sleep in Q175 Hom mice at 9 (top) and 12 months of age (bottom). <b>C.</b> 9 (top) and 12 month (bottom) old Q175 Hom mice have more fragmented daytime sleep, with increased number of sleep episodes. <b>D.</b> Sleep episodes in Q175 Hom mice are also shorter in duration. * indicates significant difference (<i>P</i><0.05) between WT and Q175 Hom mice and <sup>∧</sup> indicates differences (<i>P</i><0.05) between Q175 Het and Hom mice.</p
Sleep science is entering a new era, thanks to new data-driven analysis approaches that, combined wi...
<p>(A) Time course for amount of wake (top) and SWS (middle) was not different between the two genot...
Objective: The link between alterations in circadian rhythms and depression are well established, bu...
<p>Hourly time courses (<b>A</b>) and cumulative percent duration (<b>B</b> and <b>C</b>) of wake, N...
<p><b>A.</b> Representative double plotted actograms of wheel running activity from age-matched WT (...
<p><b>A.</b> Representative double plotted actograms of wheel running activity from age-matched WT (...
<p>(A,D). Summed power for β (15–40 Hz) and θ (4–8 Hz) oscillations. B and C: peak β frequency (Hz) ...
judgment, problem solving, creativity, memory, and mood is powerfully modulated by brain state, part...
<p>A, Number and duration of NREM bouts in the last 6± SEM from each genotype (N = 6 for each group)...
STUDY OBJECTIVES: This study describes high-throughput phenotyping strategies for sleep and circadia...
<div>A, Elevated plus maze test. Qrfp-/- mice showed fewer entries into the open arms, and spent a s...
(A) Percentage of recorded time spent in vigilance states of P10 through P21 mice. Older mice displa...
<p>Averages± standard deviations shown. Values are given for the average plus/minus standard deviati...
<div><p>Sleep science is entering a new era, thanks to new data-driven analysis approaches that, com...
<p>A) Group means (± SEM) of the total time spend in different vigilance states over 24 h LD periods...
Sleep science is entering a new era, thanks to new data-driven analysis approaches that, combined wi...
<p>(A) Time course for amount of wake (top) and SWS (middle) was not different between the two genot...
Objective: The link between alterations in circadian rhythms and depression are well established, bu...
<p>Hourly time courses (<b>A</b>) and cumulative percent duration (<b>B</b> and <b>C</b>) of wake, N...
<p><b>A.</b> Representative double plotted actograms of wheel running activity from age-matched WT (...
<p><b>A.</b> Representative double plotted actograms of wheel running activity from age-matched WT (...
<p>(A,D). Summed power for β (15–40 Hz) and θ (4–8 Hz) oscillations. B and C: peak β frequency (Hz) ...
judgment, problem solving, creativity, memory, and mood is powerfully modulated by brain state, part...
<p>A, Number and duration of NREM bouts in the last 6± SEM from each genotype (N = 6 for each group)...
STUDY OBJECTIVES: This study describes high-throughput phenotyping strategies for sleep and circadia...
<div>A, Elevated plus maze test. Qrfp-/- mice showed fewer entries into the open arms, and spent a s...
(A) Percentage of recorded time spent in vigilance states of P10 through P21 mice. Older mice displa...
<p>Averages± standard deviations shown. Values are given for the average plus/minus standard deviati...
<div><p>Sleep science is entering a new era, thanks to new data-driven analysis approaches that, com...
<p>A) Group means (± SEM) of the total time spend in different vigilance states over 24 h LD periods...
Sleep science is entering a new era, thanks to new data-driven analysis approaches that, combined wi...
<p>(A) Time course for amount of wake (top) and SWS (middle) was not different between the two genot...
Objective: The link between alterations in circadian rhythms and depression are well established, bu...