Mig6 expression correlated with erlotinib response in directly xenografted low passage lung and pancreatic tumors.

<p><b>A</b>) Effect of erlotinib on growth of directly xenografted lung tumors. Data are plotted as mean ± SEM. <b>B</b>) Real-time PCR of Mig6 on directly xenografted tumors. Data are plotted as mean ± SD after normalization with GAPDH. <b>C</b>) Immunoblot analysis of protein lysates of lung xenografts. <b>D</b>) Efficiency of erlotinib in inhibiting growth of tumor xenografts was displayed from most sensitive (left) to most resistant (right) as a bar graph. Relative expression of Mig6 in each tumor xenograft is displayed underneath the tumor growth inhibition bar as a heatmap. FC: fold change. Scale used was Log₂FC.