Relief of allodynia depends upon the ß-common receptor (ßcR).

<p><b>A.</b> Both ketamine and ARA 290 did not prevent the development of allodynia in ßcR^−/− mice. <b>B.</b> However, the effect of ketamine on nociceptive pain is unchanged in ßcR^−/− animals (treatment effect, p<0.001).