Comparison of the 3-variable Goodwin model with its variant based on multisite phosphorylation.

<p>Shown are the limit cycles obtained for the 3-variable model (black curve) and for its variant based on multisite phosphorylation, for various speeds of the phosphorylation module. The blue and red curves correspond to the cases illustrated in Figs. 5 and 6, respectively. The green curve is the limit cycle obtained when the kinetics rates of the multisite phosphorylation module are decreased by a factor 10 compared to the values given in Fig. 3. The violet dot is the stable steady state of the system when the kinetics rates of the multisite phosphorylation module are reduced by a factor 100.