PrP^Sc is present in NSC and neuroblasts areas.

<p><b>A</b>. PrP^Sc immunostaining (brown+arrow) using Saf84 anti-PrP antibody in the lateral wall (SVZ) and the surrounding of the lateral ventricle (LV). <b>B</b>. Schematic representation of the LV localisation in the mouse brain. <b>C</b>. Nestin immunostaining (brown+arrow) in the SVZ. <b>D and G</b>. Double-immunostaining of PrP^Sc (Blue) and Nestin (Brown) in the surrounding of the LV. <b>E</b>. Doublecortin (DCX) immunostaining (brown+arrow) showing neuroblasts exiting the SVZ of the lateral ventricle. <b>F and H</b> Double-immunostaining of PrP^Sc (Blue) and DCX (Brown) in the surrounding of the LV. Scale bar 20 µm.