Effect of genistein treatment on PCa cells (PC3 and DU145).

<p>(A) Genistein significantly inhibits cell viability. Cell viability was analyzed by the MTS cell proliferation assay after 4 days treatment (25 µM). **, P<0.0001. *, P<0.01. Data are presented as the mean ± SE. (B) Apoptosis assay using flow cytometry. Representative quadrant figures of control and genistein (25 µM) treated cells in PC3 (left) and DU145 (right) cells. P<0.05. (C) The typical figures of cell cycle analysis of control, or genistein (25 µM) treated cells are shown. The bar chart shown on the right of each figures represents the percentage of the cells in G0/G1, S, or G2/M phase as indicated. *P<0.05.