Lithium treatment significantly ameliorated TMT-induced clinical symptoms in mice.

<p>Lithium (50 mg/kg, i.p.) injection 0 and 24 h after TMT (2.6 mg/kg, i.p.) rescued TMT-induced seizure behaviors (<i>n</i> = 25 mice per group). The data are reported as the means±SEM. *<i>p</i><0.05, **<i>p</i><0.01, ***<i>p</i><0.001 <i>vs.</i> TMT-treated mice. TMT, TMT-treated mice; TMT+Li, TMT+lithium-treated mice.