Viral loads and cytokine levels in the brains of severe and mild cases of JaOArS982-infected mice.

<p>(A) Viral loads in the CNS of severe (weight loss: <0.75, n=8) and mild (weight loss: >0.90, n=24) cases of JaOArS982-infected B6 mice at 13 days pi. P: Mann Whitney test. (B) mRNA levels of TNF-α, IL-10, IFNγ, IL-2, IL-4 and IL-5 quantified by real-time PCR in the brain cortex of JaOArS982-infected B6 mice at 13 days pi. Uninfected group (U group, n=8), Severe group: S (n=8), Mild group with high viral load of >10⁶ pfu/g of brain tissue: MH (n=11), Mild group with low viral load of <10⁶ pfu/g of brain tissue: ML (n=13). P: Kruskal-Wallis test, <i>p</i>: Mann Whitney test.