Mean fluid source rates over the whole tumor in dependence on varying parameters.

<p> with its sub and super scripts refer to contributions to the source term as defined in (12), (23). The plotted mean values are defined simply as ensemble averages of the spatial means over the tumor. The error bars show the standard deviations within the ensemble. The subplots depict the following cases: (A) Variation of the upper vessel wall permeability bound (case (iv)). (B) Variation of the interstitial permeability coefficient (case (v)). (C) Variation of the lymphatic wall permeability in normal tissue (case (vi)). (D) Variation of the lymphatic density in the tumor given as fraction of the normal tissue lymphatic density (case (vii)). Except for in (D) the ordinate scale is relative to the base case.